SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02848

Signal sequence   MHPARPALWAAALTALTLLRGPPVARA

Length  27

Organism  Rattus norvegicus (Rat)

UniProt ID  P15473,

Motif  1..27



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02848.cif

Structure  SPKB02848.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2822.41354

Aliphatic index  112.5925926

Isoelectric point  12.80107132

Charge (pH=7)   3.088883456

Topological polar surface area  1055.39

Aromaticity  0.037037037

Average rotatable bonds  3

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  35

X logP energy  -7.30069

Hydropathy 



Literature Information


Title  Binding proteins for insulin-like growth factors in adult rat serum. Comparison with other human and rat binding proteins.

DOI  10.1016/s0006-291x(87)80136-5,

Publication Year  1987

PubMed ID  2443135,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.