SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02846

Signal sequence   MRAAPLLLARAASLSLGFLFLLFFWLDRSVLA

Length  32

Organism  Homo sapiens (Human)

UniProt ID  P15309,

Motif  1..32



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02846.cif

Structure  SPKB02846.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3580.38114

Aliphatic index  149.6875

Isoelectric point  12.19913391

Charge (pH=7)   1.99842085

Topological polar surface area  1256.11

Aromaticity  0.15625

Average rotatable bonds  3.53125

Number of hydrogen bond donors  46

Number of hydrogen bond acceptors  41

X logP energy  -3.50959

Hydropathy 



Literature Information


Title  Crystal structure of human prostatic acid phosphatase .

DOI  10.1002/(sici)1097-0045(20000215)42:3<211::aid-pros7>3.0.co;2-u,

Publication Year  2000

PubMed ID  10639192,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.