SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02845

Signal sequence   MGAPRSLLLALAAGLAVA

Length  18

Organism  Homo sapiens (Human)

UniProt ID  P15289,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02845.cif

Structure  SPKB02845.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1695.09644

Aliphatic index  157.7777778

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  631.36

Aromaticity  0

Average rotatable bonds  2.944444444

Number of hydrogen bond donors  22

Number of hydrogen bond acceptors  22

X logP energy  -4.57653

Hydropathy 



Literature Information


Title  Proteolytic processing of human lysosomal arylsulfatase A.

DOI  10.1016/0167-4838(92)90132-w,

Publication Year  1992

PubMed ID  1352993,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.