SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02843

Signal sequence   MLLPVPLLLGLLGLAAA

Length  17

Organism  Oryctolagus cuniculus (Rabbit)

UniProt ID  P15253,

Motif  1..17



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02843.cif

Structure  SPKB02843.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1675.18924

Aliphatic index  218.2352941

Isoelectric point  6.099999998

Charge (pH=7)   -0.002015701

Topological polar surface area  511.34

Aromaticity  0

Average rotatable bonds  3

Number of hydrogen bond donors  16

Number of hydrogen bond acceptors  19

X logP energy  1.2679

Hydropathy 



Literature Information


Title  Calreticulin, and not calsequestrin, is the major calcium binding protein of smooth muscle sarcoplasmic reticulum and liver endoplasmic reticulum.

DOI  NA,

Publication Year  1991

PubMed ID  2016321,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.