SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02838

Signal sequence   MRGLLVLSVLLGAVFG

Length  16

Organism  Homo sapiens (Human)

UniProt ID  P15085,

Motif  1..16



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02838.cif

Structure  SPKB02838.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1645.07944

Aliphatic index  182.5

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  581.95

Aromaticity  0.0625

Average rotatable bonds  3.375

Number of hydrogen bond donors  21

Number of hydrogen bond acceptors  20

X logP energy  -1.96573

Hydropathy 



Literature Information


Title  Further studies on the human pancreatic binary complexes involving procarboxypeptidase A.

DOI  10.1016/0014-5793(90)80665-6,

Publication Year  1990

PubMed ID  2307232,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.