SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02836

Signal sequence   MAGRARSGLLLLLLGLLALQSSCLA

Length  25

Organism  Rattus norvegicus (Rat)

UniProt ID  P14925,

Motif  1..25



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  5WM0,

Predicted Structure ID  SPKB02836.cif

Structure  SPKB02836.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2541.15184

Aliphatic index  172

Isoelectric point  10.52640717

Charge (pH=7)   1.936002961

Topological polar surface area  989.3

Aromaticity  0

Average rotatable bonds  3.48

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  34

X logP energy  -8.07986

Hydropathy 



Literature Information


Title  Purification and characterization of functional recombinant alpha-amidating enzyme secreted from mammalian cells.

DOI  NA,

Publication Year  1990

PubMed ID  2211657,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.