SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02835

Signal sequence   MSLWQPLVLVLLVLGCCFA

Length  19

Organism  Homo sapiens (Human)

UniProt ID  P14780,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02835.cif

Structure  SPKB02835.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2105.68574

Aliphatic index  174.2105263

Isoelectric point  5.826007312

Charge (pH=7)   -0.125965132

Topological polar surface area  657.44

Aromaticity  0.105263158

Average rotatable bonds  3.368421053

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  25

X logP energy  0.364

Hydropathy 



Literature Information


Title  Matrix metalloproteinase 3 (stromelysin) activates the precursor for the human matrix metalloproteinase 9.

DOI  NA,

Publication Year  1992

PubMed ID  1371271,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.