SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02828

Signal sequence   MKTLLLLAVIMIFGLLQAHG

Length  20

Organism  Homo sapiens (Human)

UniProt ID  P14555,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02828.cif

Structure  SPKB02828.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2182.79724

Aliphatic index  180.5

Isoelectric point  9.702001779

Charge (pH=7)   1.088598356

Topological polar surface area  734.24

Aromaticity  0.05

Average rotatable bonds  3.7

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  27

X logP energy  -0.5731

Hydropathy 



Literature Information


Title  The primary structure of a membrane-associated phospholipase A2 from human spleen.

DOI  10.1016/0006-291x(89)92096-2,

Publication Year  1989

PubMed ID  2775276,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.