General Information
SPKB ID SPKB02824
Signal sequence MDFPCLWLGLLLPLVAA
Length 17
Organism Homo sapiens (Human)
UniProt ID P14384,
Motif 1..17
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02824.cif
Physicochemical Information
Molecular weight 1872.35694
Aliphatic index 166.4705882
Isoelectric point 3.749971454
Charge (pH=7) -1.063543932
Topological polar surface area 564.43
Aromaticity 0.117647059
Average rotatable bonds 3.176470588
Number of hydrogen bond donors 19
Number of hydrogen bond acceptors 21
X logP energy 1.8956
Hydropathy 
Literature Information
Title Effect of mutation of two critical glutamic acid residues on the activity and stability of human carboxypeptidase M and characterization of its signal for glycosylphosphatidylinositol anchoring.
DOI 10.1042/BJ20021495,
Publication Year 2003
PubMed ID 12457462,
Patent ID NA,
