SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02822

Signal sequence   MLLSVPLLLGLLGLAAA

Length  17

Organism  Mus musculus (Mouse)

UniProt ID  P14211,

Motif  1..17



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02822.cif

Structure  SPKB02822.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1665.15074

Aliphatic index  218.2352941

Isoelectric point  6.099999998

Charge (pH=7)   -0.002015701

Topological polar surface area  540.36

Aromaticity  0

Average rotatable bonds  3.117647059

Number of hydrogen bond donors  18

Number of hydrogen bond acceptors  20

X logP energy  -0.246

Hydropathy 



Literature Information


Title  Multiple zones in the sequence of calreticulin (CRP55, calregulin, HACBP), a major calcium binding ER/SR protein.

DOI  10.1002/j.1460-2075.1989.tb08530.x,

Publication Year  1989

PubMed ID  2583110,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.