SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02820

Signal sequence   MARGAALALLLFGLLGVLVAAP

Length  22

Organism  Homo sapiens (Human)

UniProt ID  P14209,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02820.cif

Structure  SPKB02820.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2137.69814

Aliphatic index  177.7272727

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  727.53

Aromaticity  0.045454545

Average rotatable bonds  3.045454545

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  25

X logP energy  -2.00733

Hydropathy 



Literature Information


Title  The E2 antigen, a 32 kd glycoprotein involved in T-cell adhesion processes, is the MIC2 gene product.

DOI  10.1002/j.1460-2075.1989.tb08485.x,

Publication Year  1989

PubMed ID  2479542,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.