SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02818

Signal sequence   MKTLLLLLLVLLELGEAQG

Length  19

Organism  Homo sapiens (Human)

UniProt ID  P14091,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02818.cif

Structure  SPKB02818.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2067.59854

Aliphatic index  205.2631579

Isoelectric point  4.258147297

Charge (pH=7)   -0.998760489

Topological polar surface area  751.06

Aromaticity  0

Average rotatable bonds  3.842105263

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  26

X logP energy  -1.2637

Hydropathy 



Literature Information


Title  Isolation and biochemical characterization of procathepsin E from human erythrocyte membranes.

DOI  10.1006/abbi.1993.1361,

Publication Year  1993

PubMed ID  8346912,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.