SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02817

Signal sequence   MGIQGGSVLFGLLLVLAVFCHSGHS

Length  25

Organism  Homo sapiens (Human)

UniProt ID  P13987,

Motif  1..25



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  8B0F,

Predicted Structure ID  SPKB02817.cif

Structure  SPKB02817.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2543.03984

Aliphatic index  132.4

Isoelectric point  7.523974965

Charge (pH=7)   0.117827765

Topological polar surface area  922.86

Aromaticity  0.08

Average rotatable bonds  3.28

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  34

X logP energy  -7.2027

Hydropathy 



Literature Information


Title  The glycosylation of the complement regulatory protein, human erythrocyte CD59.

DOI  10.1074/jbc.272.11.7229,

Publication Year  1997

PubMed ID  9054419,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.