SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02814

Signal sequence   MGVLLTQRTLLSLVLALLFPSMASM

Length  25

Organism  Homo sapiens (Human)

UniProt ID  P13725,

Motif  1..25



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02814.cif

Structure  SPKB02814.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2706.39924

Aliphatic index  156

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  959.07

Aromaticity  0.04

Average rotatable bonds  3.56

Number of hydrogen bond donors  34

Number of hydrogen bond acceptors  36

X logP energy  -5.33903

Hydropathy 



Literature Information


Title  Identification of a major growth factor for AIDS-Kaposi's sarcoma cells as oncostatin M.

DOI  10.1126/science.1542792,

Publication Year  1992

PubMed ID  1542792,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.