General Information
SPKB ID SPKB02811
Signal sequence MARRSVLYFILLNALINKGQA
Length 21
Organism Homo sapiens (Human)
UniProt ID P13671,
Motif 1..21
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 8B0F,
Predicted Structure ID SPKB02811.cif
Physicochemical Information
Molecular weight 2391.90334
Aliphatic index 139.5238095
Isoelectric point 11.53052052
Charge (pH=7) 2.996832229
Topological polar surface area 964.87
Aromaticity 0.095238095
Average rotatable bonds 3.857142857
Number of hydrogen bond donors 34
Number of hydrogen bond acceptors 31
X logP energy -6.67376
Hydropathy 
Literature Information
Title Complete primary structure and functional characterization of the sixth component of the human complement system. Identification of the C5b-binding domain in complement C6.
DOI NA,
Publication Year 1989
PubMed ID 2808363,
Patent ID NA,
