SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02803

Signal sequence   MKVSAAALAVILIATALCAPASA

Length  23

Organism  Homo sapiens (Human)

UniProt ID  P13501,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02803.cif

Structure  SPKB02803.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2156.67034

Aliphatic index  149.1304348

Isoelectric point  8.545189979

Charge (pH=7)   0.93571455

Topological polar surface area  781.44

Aromaticity  0

Average rotatable bonds  2.913043478

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  30

X logP energy  -6.531

Hydropathy 



Literature Information


Title  Cytokine RANTES released by thrombin-stimulated platelets is a potent attractant for human eosinophils.

DOI  10.1084/jem.176.2.587,

Publication Year  1992

PubMed ID  1380064,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.