SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02802

Signal sequence   MKVSAALLCLLLIAATFIPQGLA

Length  23

Organism  Homo sapiens (Human)

UniProt ID  P13500,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02802.cif

Structure  SPKB02802.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2357.98174

Aliphatic index  170

Isoelectric point  8.545189979

Charge (pH=7)   0.93571455

Topological polar surface area  804.3

Aromaticity  0.043478261

Average rotatable bonds  3.304347826

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  30

X logP energy  -2.981

Hydropathy 



Literature Information


Title  Complete amino acid sequence of a human monocyte chemoattractant, a putative mediator of cellular immune reactions.

DOI  10.1073/pnas.86.6.1850,

Publication Year  1989

PubMed ID  2648385,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.