SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02797

Signal sequence   MDCRKMARFSYSVIWIMAISKVFELGLVAG

Length  30

Organism  Homo sapiens (Human)

UniProt ID  P13385,

Motif  1..30



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02797.cif

Structure  SPKB02797.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3423.17114

Aliphatic index  104

Isoelectric point  9.404163101

Charge (pH=7)   1.936784086

Topological polar surface area  1254.37

Aromaticity  0.133333333

Average rotatable bonds  3.8

Number of hydrogen bond donors  47

Number of hydrogen bond acceptors  45

X logP energy  -6.57376

Hydropathy 



Literature Information


Title  Signal peptide prediction based on analysis of experimentally verified cleavage sites.

DOI  10.1110/ps.04682504,

Publication Year  2004

PubMed ID  15340161,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.