SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02795

Signal sequence   MGSGPRGALSLLLLLLAPPSRPAAG

Length  25

Organism  Homo sapiens (Human)

UniProt ID  P13224,

Motif  1..25



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02795.cif

Structure  SPKB02795.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2415.92284

Aliphatic index  125.2

Isoelectric point  12.50010931

Charge (pH=7)   1.997977677

Topological polar surface area  911.05

Aromaticity  0

Average rotatable bonds  2.92

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  32

X logP energy  -8.75726

Hydropathy 



Literature Information


Title  Isolation and characterization of the alpha and beta chains of human platelet glycoprotein Ib.

DOI  10.1016/0006-291x(87)90963-6,

Publication Year  1987

PubMed ID  3632685,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.