SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02794

Signal sequence   MDLQKVLPQMILLLLFLNLSPLGGHS

Length  26

Organism  Rattus norvegicus (Rat)

UniProt ID  P13205,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02794.cif

Structure  SPKB02794.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2891.56624

Aliphatic index  161.1538462

Isoelectric point  7.549350682

Charge (pH=7)   0.089044841

Topological polar surface area  1034.97

Aromaticity  0.038461538

Average rotatable bonds  3.692307692

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  37

X logP energy  -4.3801

Hydropathy 



Literature Information


Title  Isolation and identification of rat brain natriuretic peptides in cardiac atrium.

DOI  10.1016/0006-291x(89)92125-6,

Publication Year  1989

PubMed ID  2673236,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.