SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02791

Signal sequence   MKFCTAVAVAMGMGPAFAPKVAE

Length  23

Organism  Megalodesulfovibrio gigas (Desulfovibrio gigas)

UniProt ID  P12943,

Motif  1..23



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02791.cif

Structure  SPKB02791.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2327.86164

Aliphatic index  63.91304348

Isoelectric point  8.540504393

Charge (pH=7)   0.937194639

Topological polar surface area  795.51

Aromaticity  0.086956522

Average rotatable bonds  3.130434783

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  32

X logP energy  -5.3954

Hydropathy 



Literature Information


Title  Cloning, characterization, and sequencing of the genes encoding the large and small subunits of the periplasmic [NiFe]hydrogenase of Desulfovibrio gigas.

DOI  10.1089/dna.1987.6.539,

Publication Year  1987

PubMed ID  3322743,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.