SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02790

Signal sequence   MLPRLGGPALPLLLPSLLLLLLLGAGGCGPGVRA

Length  34

Organism  Rattus norvegicus (Rat)

UniProt ID  P12843,

Motif  1..34



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02790.cif

Structure  SPKB02790.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3320.18784

Aliphatic index  166.4705882

Isoelectric point  10.52640717

Charge (pH=7)   1.936002961

Topological polar surface area  1123.7

Aromaticity  0

Average rotatable bonds  3

Number of hydrogen bond donors  38

Number of hydrogen bond acceptors  40

X logP energy  -5.13576

Hydropathy 



Literature Information


Title  Identification of a novel binding protein for insulin-like growth factors in adult rat serum.

DOI  10.1016/0006-291x(89)91053-x,

Publication Year  1989

PubMed ID  2480123,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.