General Information
SPKB ID SPKB02788
Signal sequence MGAASGRRGPGLLLPLPLLLLLPPQPALA
Length 29
Organism Homo sapiens (Human)
UniProt ID P12821,
Motif 1..29
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 9CLX,
Predicted Structure ID SPKB02788.cif
Physicochemical Information
Molecular weight 2903.60874
Aliphatic index 148.2758621
Isoelectric point 12.50010931
Charge (pH=7) 1.997977677
Topological polar surface area 1012.5
Aromaticity 0
Average rotatable bonds 2.965517241
Number of hydrogen bond donors 32
Number of hydrogen bond acceptors 35
X logP energy -5.38646
Hydropathy
Literature Information
Title Purification of human lung angiotensin-converting enzyme by high-performance liquid chromatography: properties and N-terminal amino acid sequence.
DOI 10.1093/oxfordjournals.jbchem.a122871,
Publication Year 1989
PubMed ID 2558109,
Patent ID NA,