SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02786

Signal sequence   MSWSSHPPSVIFYILSLLSSACLA

Length  24

Organism  Bos taurus (Bovine)

UniProt ID  P12799,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02786.cif

Structure  SPKB02786.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2610.08094

Aliphatic index  117.9166667

Isoelectric point  7.355498302

Charge (pH=7)   0.02606826

Topological polar surface area  921.35

Aromaticity  0.125

Average rotatable bonds  3.208333333

Number of hydrogen bond donors  34

Number of hydrogen bond acceptors  36

X logP energy  -6.9567

Hydropathy 



Literature Information


Title  Disulfide-linked cyanogen bromide peptides of bovine fibrinogen. II. Isolation and sequence analysis of the chain constituents from the amino terminal region.

DOI  10.1016/0005-2795(77)90017-4,

Publication Year  1977

PubMed ID  836881,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.