SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02784

Signal sequence   MKFQHTFIALLSLLTYANA

Length  19

Organism  Dictyostelium discoideum (Social amoeba)

UniProt ID  P12729,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02784.cif

Structure  SPKB02784.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2182.60854

Aliphatic index  118.4210526

Isoelectric point  9.300695891

Charge (pH=7)   1.087747942

Topological polar surface area  808.92

Aromaticity  0.157894737

Average rotatable bonds  3.684210526

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  29

X logP energy  -4.4087

Hydropathy 



Literature Information


Title  Structural characterization of Dictyostelium discoideum prespore-specific gene D19 and of its product, cell surface glycoprotein PsA.

DOI  10.1128/mcb.8.8.3458-3466.1988,

Publication Year  1988

PubMed ID  2850494,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.