SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02783

Signal sequence   MVPKLFTSQICLLLLLGLMGVEGSLHA

Length  27

Organism  Homo sapiens (Human)

UniProt ID  P12724,

Motif  1..27



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02783.cif

Structure  SPKB02783.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2884.58974

Aliphatic index  155.1851852

Isoelectric point  7.359398109

Charge (pH=7)   0.028398763

Topological polar surface area  1006.91

Aromaticity  0.037037037

Average rotatable bonds  3.555555556

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  38

X logP energy  -4.5805

Hydropathy 



Literature Information


Title  Antibiotic proteins of human polymorphonuclear leukocytes.

DOI  10.1073/pnas.86.14.5610,

Publication Year  1989

PubMed ID  2501794,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.