SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02780

Signal sequence   MKRTHLFIAGLYLLASCRA

Length  19

Organism  Canis lupus familiaris (Dog) (Canis familiaris)

UniProt ID  P12637,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02780.cif

Structure  SPKB02780.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2164.65804

Aliphatic index  118.4210526

Isoelectric point  10.45691448

Charge (pH=7)   3.025766604

Topological polar surface area  826.31

Aromaticity  0.105263158

Average rotatable bonds  3.736842105

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  29

X logP energy  -5.08536

Hydropathy 



Literature Information


Title  Characterization of cardiac calsequestrin.

DOI  10.1021/bi00394a038,

Publication Year  1987

PubMed ID  3427023,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.