SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02778

Signal sequence   MRFAVGALLACAALGLCLA

Length  19

Organism  Rattus norvegicus (Rat)

UniProt ID  P12346,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02778.cif

Structure  SPKB02778.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1864.35574

Aliphatic index  149.4736842

Isoelectric point  8.231408964

Charge (pH=7)   0.874031556

Topological polar surface area  649.02

Aromaticity  0.052631579

Average rotatable bonds  3.105263158

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  24

X logP energy  -3.48793

Hydropathy 



Literature Information


Title  Properties of the transferrin associated with rat intestinal mucosa.

DOI  10.1016/0304-4165(88)90081-5,

Publication Year  1988

PubMed ID  3046665,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.