General Information
SPKB ID SPKB02777
Signal sequence MAPAMESPTLLCVALLFFAPDGVLA
Length 25
Organism Homo sapiens (Human)
UniProt ID P12319,
Motif 1..25
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 8K7R,
Predicted Structure ID SPKB02777.cif
Physicochemical Information
Molecular weight 2578.13804
Aliphatic index 121.2
Isoelectric point 3.550065871
Charge (pH=7) -2.06176881
Topological polar surface area 850.41
Aromaticity 0.08
Average rotatable bonds 3.04
Number of hydrogen bond donors 28
Number of hydrogen bond acceptors 33
X logP energy -3.5405
Hydropathy
Literature Information
Title High-level expression of the truncated alpha chain of human high-affinity receptor for IgE as a soluble form by baculovirus-infected insect cells. Biochemical characterization of the recombinant product.
DOI 10.1111/j.1432-1033.1994.tb18660.x,
Publication Year 1994
PubMed ID 8125119,
Patent ID NA,