SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02773

Signal sequence   MRLLQLLFRASPATLLLVLCLQLGANKA

Length  28

Organism  Homo sapiens (Human)

UniProt ID  P12273,

Motif  1..28



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02773.cif

Structure  SPKB02773.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3067.83124

Aliphatic index  163.9285714

Isoelectric point  11.48119255

Charge (pH=7)   2.935707927

Topological polar surface area  1159.78

Aromaticity  0.035714286

Average rotatable bonds  3.678571429

Number of hydrogen bond donors  41

Number of hydrogen bond acceptors  39

X logP energy  -6.81726

Hydropathy 



Literature Information


Title  Primary structure of a new actin-binding protein from human seminal plasma.

DOI  10.1111/j.1432-1033.1991.tb15873.x,

Publication Year  1991

PubMed ID  2013294,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.