SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02772

Signal sequence   MGLEFFFKFGYAFLTITLMIMIWMSLARA

Length  29

Organism  Drosophila melanogaster (Fruit fly)

UniProt ID  P12024,

Motif  1..29



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02772.cif

Structure  SPKB02772.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3450.27934

Aliphatic index  104.4827586

Isoelectric point  9.297359792

Charge (pH=7)   0.998610663

Topological polar surface area  1100.05

Aromaticity  0.24137931

Average rotatable bonds  3.827586207

Number of hydrogen bond donors  40

Number of hydrogen bond acceptors  41

X logP energy  0.52707

Hydropathy 



Literature Information


Title  Neuronal development in the Drosophila retina: monoclonal antibodies as molecular probes.

DOI  10.1016/0092-8674(84)90069-2,

Publication Year  1984

PubMed ID  6420071,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.