SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02768

Signal sequence   MPGGPGVLQALPATIFLLFLLSAVYLGPGCQA

Length  32

Organism  Homo sapiens (Human)

UniProt ID  P11912,

Motif  1..32



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  7XQ8,

Predicted Structure ID  SPKB02768.cif

Structure  SPKB02768.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3215.90244

Aliphatic index  128.125

Isoelectric point  5.919503212

Charge (pH=7)   -0.064840831

Topological polar surface area  1077.13

Aromaticity  0.09375

Average rotatable bonds  2.96875

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  40

X logP energy  -5.61

Hydropathy 



Literature Information


Title  Isolation and chemical characterization of the human B29 and mb-1 proteins of the B cell antigen receptor complex.

DOI  10.1016/0161-5890(94)90061-2,

Publication Year  1994

PubMed ID  7514267,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.