SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02765

Signal sequence   MKLAVTLTLVTLALCCSSASA

Length  21

Organism  Homo sapiens (Human)

UniProt ID  P11684,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02765.cif

Structure  SPKB02765.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2096.58684

Aliphatic index  139.5238095

Isoelectric point  8.229691165

Charge (pH=7)   0.873739834

Topological polar surface area  792.72

Aromaticity  0

Average rotatable bonds  3.238095238

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  32

X logP energy  -8.4226

Hydropathy 



Literature Information


Title  Newly identified proteins in human nasal lavage fluid from non-smokers and smokers using two-dimensional gel electrophoresis and peptide mass fingerprinting.

DOI  NA,

Publication Year  2002

PubMed ID  11788998,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.