SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02763

Signal sequence   MRFSCLALLPGVALLLASALLASA

Length  24

Organism  Rattus norvegicus (Rat)

UniProt ID  P11598,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02763.cif

Structure  SPKB02763.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2401.99454

Aliphatic index  167.0833333

Isoelectric point  8.549912035

Charge (pH=7)   0.936006272

Topological polar surface area  846.42

Aromaticity  0.041666667

Average rotatable bonds  3.166666667

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  31

X logP energy  -5.00373

Hydropathy 



Literature Information


Title  Purification and characterization of a new isozyme of thiol:protein-disulfide oxidoreductase from rat hepatic microsomes. Relationship of this isozyme to cytosolic phosphatidylinositol-specific phospholipase C form 1A.

DOI  NA,

Publication Year  1991

PubMed ID  1657921,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.