SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02761

Signal sequence   MHLTPHWIPLVASLGLLAGGSFASA

Length  25

Organism  Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

UniProt ID  P11439,

Motif  1..25



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02761.cif

Structure  SPKB02761.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2547.01284

Aliphatic index  121.2

Isoelectric point  7.714356232

Charge (pH=7)   0.179802481

Topological polar surface area  898.21

Aromaticity  0.08

Average rotatable bonds  3

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  33

X logP energy  -6.0386

Hydropathy 



Literature Information


Title  Cloning, nucleotide sequence, and expression in Escherichia coli of the exotoxin A structural gene of Pseudomonas aeruginosa.

DOI  10.1073/pnas.81.9.2645,

Publication Year  1984

PubMed ID  6201861,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.