SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02758

Signal sequence   MSLFPSLPLLLLSMVAASYS

Length  20

Organism  Homo sapiens (Human)

UniProt ID  P11226,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02758.cif

Structure  SPKB02758.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2140.62404

Aliphatic index  141.5

Isoelectric point  6.093198033

Charge (pH=7)   -0.002866115

Topological polar surface area  720.02

Aromaticity  0.1

Average rotatable bonds  3.25

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  29

X logP energy  -3.747

Hydropathy 



Literature Information


Title  Structure and function of mannan-binding proteins isolated from human liver and serum.

DOI  10.1093/oxfordjournals.jbchem.a124471,

Publication Year  1994

PubMed ID  7982896,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.