SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02757

Signal sequence   MMMRFLSAVVIMSSAMAVGLVSA

Length  23

Organism  Urtica dioica (Great nettle) (Stinging nettle)

UniProt ID  P11218,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02757.cif

Structure  SPKB02757.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2403.03084

Aliphatic index  118.6956522

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  846.34

Aromaticity  0.043478261

Average rotatable bonds  3.47826087

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  34

X logP energy  -6.22213

Hydropathy 



Literature Information


Title  The primary structure of stinging nettle (Urtica dioica) agglutinin. A two-domain member of the hevein family.

DOI  10.1016/0014-5793(92)80231-5,

Publication Year  1992

PubMed ID  1544484,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.