SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02756

Signal sequence   MALRVLLLTALTLCHG

Length  16

Organism  Homo sapiens (Human)

UniProt ID  P11215,

Motif  1..16



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02756.cif

Structure  SPKB02756.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1725.18394

Aliphatic index  176.875

Isoelectric point  8.557478416

Charge (pH=7)   1.026915363

Topological polar surface area  630.86

Aromaticity  0

Average rotatable bonds  3.5

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  23

X logP energy  -3.05233

Hydropathy 



Literature Information


Title  N-terminal sequence of human leukocyte glycoprotein Mo1: conservation across species and homology to platelet IIb/IIIa.

DOI  10.1016/0167-4838(86)90037-3,

Publication Year  1986

PubMed ID  3539202,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.