SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02754

Signal sequence   MDTSPLCFSILLVLCIFIQSSA

Length  22

Organism  Homo sapiens (Human)

UniProt ID  P11150,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02754.cif

Structure  SPKB02754.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2401.91974

Aliphatic index  141.8181818

Isoelectric point  3.749955547

Charge (pH=7)   -1.125518648

Topological polar surface area  847.17

Aromaticity  0.090909091

Average rotatable bonds  3.454545455

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  33

X logP energy  -5.7278

Hydropathy 



Literature Information


Title  Isolation and cDNA sequence of human postheparin plasma hepatic triglyceride lipase.

DOI  NA,

Publication Year  1988

PubMed ID  2839510,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.