SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02753

Signal sequence   MKLSLVAAMLLLLSAARA

Length  18

Organism  Homo sapiens (Human)

UniProt ID  P11021,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02753.cif

Structure  SPKB02753.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1872.40144

Aliphatic index  173.8888889

Isoelectric point  11.65177567

Charge (pH=7)   1.997685954

Topological polar surface area  686.4

Aromaticity  0

Average rotatable bonds  3.555555556

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  25

X logP energy  -3.44493

Hydropathy 



Literature Information


Title  Heat shock proteins bind calcitonin.

DOI  10.1210/endo-126-1-672,

Publication Year  1990

PubMed ID  2294010,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.