SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02752

Signal sequence   MWLCALVWASLAVCPIWG

Length  18

Organism  Rattus norvegicus (Rat)

UniProt ID  P10959,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02752.cif

Structure  SPKB02752.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2019.51104

Aliphatic index  135.5555556

Isoelectric point  5.826007312

Charge (pH=7)   -0.125965132

Topological polar surface area  616.83

Aromaticity  0.166666667

Average rotatable bonds  3.111111111

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  23

X logP energy  1.1106

Hydropathy 



Literature Information


Title  Molecular cloning and nucleotide sequence of cDNA of microsomal carboxyesterase E1 of rat liver.

DOI  10.1093/oxfordjournals.jbchem.a122553,

Publication Year  1988

PubMed ID  3235453,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.