General Information
SPKB ID SPKB02751
Signal sequence MMKTLLLFVGLLLTWESGQVLG
Length 22
Organism Homo sapiens (Human)
UniProt ID P10909,
Motif 1..22
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02751.cif
Physicochemical Information
Molecular weight 2450.03564
Aliphatic index 150.4545455
Isoelectric point 6.408795646
Charge (pH=7) -0.000535612
Topological polar surface area 857.31
Aromaticity 0.090909091
Average rotatable bonds 3.727272727
Number of hydrogen bond donors 30
Number of hydrogen bond acceptors 31
X logP energy -2.4059
Hydropathy
Literature Information
Title Characterization of a human high density lipoprotein-associated protein, NA1/NA2. Identity with SP-40,40, an inhibitor of complement-mediated cytolysis.
Publication Year 1991
PubMed ID 1903064,
Patent ID NA,