General Information
SPKB ID SPKB02748
Signal sequence MATCLFLLGLFLLLPRPVPA
Length 20
Organism Mus musculus (Mouse)
UniProt ID P10820,
Motif 1..20
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02748.cif
Physicochemical Information
Molecular weight 2185.80044
Aliphatic index 161
Isoelectric point 8.549912035
Charge (pH=7) 0.936006272
Topological polar surface area 671.98
Aromaticity 0.1
Average rotatable bonds 3.2
Number of hydrogen bond donors 23
Number of hydrogen bond acceptors 25
X logP energy 0.59037
Hydropathy
Literature Information
Title The primary structure of the lymphocyte pore-forming protein perforin: partial amino acid sequencing and determination of isoelectric point.
DOI 10.1016/s0006-291x(88)80905-7,
Publication Year 1988
PubMed ID 3190678,
Patent ID NA,