General Information
SPKB ID SPKB02743
Signal sequence MSSAARSRLTRATRQEMLFLALLLLPVVVA
Length 30
Organism Homo sapiens (Human)
UniProt ID P10720,
Motif 1..30
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02743.cif
Physicochemical Information
Molecular weight 3315.04234
Aliphatic index 136.6666667
Isoelectric point 12.50005466
Charge (pH=7) 2.999746177
Topological polar surface area 1327.57
Aromaticity 0.033333333
Average rotatable bonds 3.666666667
Number of hydrogen bond donors 49
Number of hydrogen bond acceptors 44
X logP energy -10.97532
Hydropathy
Literature Information
Title Platelets release CXCL4L1, a nonallelic variant of the chemokine platelet factor-4/CXCL4 and potent inhibitor of angiogenesis.
DOI 10.1161/01.RES.0000146674.38319.07,
Publication Year 2004
PubMed ID 15459074,
Patent ID NA,