General Information
SPKB ID SPKB02741
Signal sequence MIYTMKKVHALWASVCLLLNLAPAPLNA
Length 28
Organism Homo sapiens (Human)
UniProt ID P10646,
Motif 1..28
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 7V1N,
Predicted Structure ID SPKB02741.cif
Physicochemical Information
Molecular weight 3082.81704
Aliphatic index 136.0714286
Isoelectric point 9.407025159
Charge (pH=7) 2.025478192
Topological polar surface area 1074.82
Aromaticity 0.071428571
Average rotatable bonds 3.428571429
Number of hydrogen bond donors 37
Number of hydrogen bond acceptors 40
X logP energy -4.3095
Hydropathy
Literature Information
Title Signal peptide prediction based on analysis of experimentally verified cleavage sites.
DOI 10.1110/ps.04682504,
Publication Year 2004
PubMed ID 15340161,
Patent ID NA,