SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02739

Signal sequence   MIRAAPPPLFLLLLLLLLLVSWASRGEA

Length  28

Organism  Homo sapiens (Human)

UniProt ID  P10619,

Motif  1..28



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02739.cif

Structure  SPKB02739.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3074.84774

Aliphatic index  177.8571429

Isoelectric point  10.39777148

Charge (pH=7)   0.9997528

Topological polar surface area  1040

Aromaticity  0.071428571

Average rotatable bonds  3.392857143

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  35

X logP energy  -1.02366

Hydropathy 



Literature Information


Title  Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.

DOI  10.1038/nbt810,

Publication Year  2003

PubMed ID  12665801,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.