SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02737

Signal sequence   MLDASGCSWAMWTWALLQLLLLVGPGGC

Length  28

Organism  Mus musculus (Mouse)

UniProt ID  P10493,

Motif  1..28



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02737.cif

Structure  SPKB02737.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2993.60754

Aliphatic index  118.5714286

Isoelectric point  3.749955547

Charge (pH=7)   -1.125518648

Topological polar surface area  1028.68

Aromaticity  0.107142857

Average rotatable bonds  3.25

Number of hydrogen bond donors  38

Number of hydrogen bond acceptors  38

X logP energy  -4.7985

Hydropathy 



Literature Information


Title  Amino acid sequence and domain structure of entactin. Homology with epidermal growth factor precursor and low density lipoprotein receptor.

DOI  10.1083/jcb.107.6.2749,

Publication Year  1988

PubMed ID  3264556,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.