SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02736

Signal sequence   MKKIVSLVCVLVMLVSILGSFSVVAASPVKGFQV

Length  34

Organism  Acetivibrio thermocellus (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) (Clostridium thermocellum)

UniProt ID  P10477,

Motif  1..34



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02736.cif

Structure  SPKB02736.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3550.46434

Aliphatic index  151.4705882

Isoelectric point  10.51301932

Charge (pH=7)   2.935124482

Topological polar surface area  1237.13

Aromaticity  0.058823529

Average rotatable bonds  3.470588235

Number of hydrogen bond donors  44

Number of hydrogen bond acceptors  47

X logP energy  -7.0785

Hydropathy 



Literature Information


Title  Conserved reiterated domains in Clostridium thermocellum endoglucanases are not essential for catalytic activity.

DOI  10.1016/0378-1119(88)90375-7,

Publication Year  1988

PubMed ID  3066698,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.