General Information
SPKB ID SPKB02735
Signal sequence MRSSAALALLLCAGQVFA
Length 18
Organism Rattus norvegicus (Rat)
UniProt ID P10354,
Motif 1..18
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02735.cif
Physicochemical Information
Molecular weight 1822.21394
Aliphatic index 130.5555556
Isoelectric point 8.549912035
Charge (pH=7) 0.936006272
Topological polar surface area 703.47
Aromaticity 0.055555556
Average rotatable bonds 3.277777778
Number of hydrogen bond donors 26
Number of hydrogen bond acceptors 25
X logP energy -6.34983
Hydropathy
Literature Information
Title beta-Granins: 21 kDa co-secreted peptides of the insulin granule closely related to adrenal medullary chromogranin A.
DOI 10.1016/0014-5793(85)80398-7,
Publication Year 1985
PubMed ID 3896848,
Patent ID NA,