SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02732

Signal sequence   MVPKLFTSQICLLLLLGLLAVEGSLHV

Length  27

Organism  Homo sapiens (Human)

UniProt ID  P10153,

Motif  1..27



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  5E13,

Predicted Structure ID  SPKB02732.cif

Structure  SPKB02732.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2908.63724

Aliphatic index  180.3703704

Isoelectric point  7.359398109

Charge (pH=7)   0.028398763

Topological polar surface area  1006.91

Aromaticity  0.037037037

Average rotatable bonds  3.555555556

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  37

X logP energy  -3.2629

Hydropathy 



Literature Information


Title  Amino acid sequence of the nonsecretory ribonuclease of human urine.

DOI  10.1021/bi00412a046,

Publication Year  1988

PubMed ID  3166997,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.